Parasites have mastered the art of survival by making other animals their permanent homes. These microscopic invaders live entirely inside their hosts, relying on them for food, shelter, and even transportation. Some cause devastating diseases, while others form surprising partnerships that benefit both creatures.
This article is for educational purposes only and does not provide medical advice. If you suspect parasitic infection, consult a qualified healthcare professional.
1. Plasmodium spp.

Malaria claims hundreds of thousands of lives annually, all thanks to this single-celled parasite. Plasmodium travels through mosquito bites, entering human bloodstreams where it invades red blood cells.
Once inside, it multiplies rapidly, bursting cells open and releasing more parasites. This cycle causes fever, chills, and potentially fatal complications. Five species infect humans, with Plasmodium falciparum being the deadliest culprit worldwide.
2. Trypanosoma brucei

African sleeping sickness sounds mysterious, and its cause is equally fascinating. Tsetse flies transmit this corkscrew-shaped parasite that swims through blood and lymph fluid using a whip-like tail.
Eventually, it crosses into the brain, causing confusion, sleep disturbances, and personality changes. Without treatment, the infection proves fatal. This parasite constantly changes its surface proteins, making it incredibly difficult for immune systems to recognize and eliminate.
3. Wolbachia pipientis

Not all parasites are villains. Wolbachia infects up to 60% of insect species, living exclusively inside their cells without ever leaving.
This bacterium manipulates reproduction in bizarre ways, sometimes killing male embryos or changing males into females. Scientists now use Wolbachia to fight dengue fever by infecting mosquitoes, which then become unable to transmit the virus. This remarkable strategy has reduced disease rates in several countries successfully.
4. Buchnera aphidicola

Aphids would starve without this bacterial partner living in specialized cells called bacteriocytes. Plant sap lacks essential amino acids that aphids need for survival.
Buchnera manufactures these nutrients, allowing aphids to thrive on their limited diet. In return, aphids provide shelter and food. This relationship has lasted over 100 million years, with neither organism able to survive independently anymore. The bacterium has lost many genes, becoming completely dependent.
5. Carsonella ruddii

Meet the organism with one of the smallest genomes ever discovered. Carsonella lives inside sap-sucking insects called psyllids, producing amino acids they cannot obtain from plants.
Its genome is so reduced that scientists debate whether it is still truly a bacterium or something new entirely. With only 160,000 DNA base pairs, it has fewer genes than some viruses. This extreme simplification shows how far symbiosis can go.
6. Trichinella spiralis

Raw or undercooked pork can harbour this roundworm that causes trichinosis. After being eaten, larvae mature in the intestines, then produce offspring that burrow through the intestinal wall.
These new larvae travel through blood vessels to muscles, where they coil up and form protective cysts. Infected muscle tissue becomes painful and inflamed. Proper cooking kills the parasites, making pork safe to eat and preventing this uncomfortable infection.
7. Wuchereria bancrofti

Elephantiasis, a condition causing extreme limb swelling, stems from this threadlike worm transmitted by mosquitoes. Adult worms live in lymph vessels for years, blocking fluid drainage and causing massive tissue enlargement.
They release millions of microscopic larvae into the bloodstream, timing their appearance to coincide with mosquito feeding times. Over 120 million people worldwide carry this infection, though many show no symptoms despite harboring living worms.
8. Myxobolus cerebralis

Whirling disease devastates trout populations, causing fish to swim in circles before dying. This microscopic parasite invades cartilage in young fish, deforming their skeletons and damaging nerves that control swimming.
Myxobolus requires two hosts: fish and tiny aquatic worms. Spores released from dead fish infect worms, which then release different spores that infect new fish. Hatcheries and wild populations have suffered massive losses from this persistent parasite.